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Featuring guest: Jimmy Moore
Author of the new book Keto Clarity
Want some extra help? Have you been trying Paleo for a while but have questions or aren’t sure what the right exercise program is for you? Or maybe you just want a 30-day meal plan and shopping list to make things easier? We’ve created a getting started guide to help you through your first 30 days.
Robb Wolf is a former research biochemist and 2X New York Times/Wall Street Journal Best-selling author of The Paleo Solution and Wired To Eat. Along with Diana Rodgers, he co-authored the book, Sacred Cow, which explains why well-raised meat is good for us and good for the planet. Robb has transformed the lives of hundreds of thousands of people around the world via his top-ranked iTunes podcast, books, and seminars. He also co-founded the 1st and 4th CrossFit affiliate gyms in the world, The Healthy Rebellion community platform, and is the co-founder of DrinkLMNT Electrolytes.
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Hey Robb. Have you looked into the hypothesis that High cholesterol and particle numbers in the APO E4 is a protective measure for the brain? Some research indicates that AD patients with APO E4 have lower levels of “cholesterol, phospholipids, and fatty acids in cerebrospinal fluid of Alzheimer disease patients”
http://www.ncbi.nlm.nih.gov/pubmed/9772023?dopt=Abstract
In this study high cholesterol levels in middle age is correlated with AD in later life but cholesterol levels drop before symptoms of AD are reported.
http://www.ncbi.nlm.nih.gov/pubmed/9549720?dopt=Abstract
People with APO E4 may have high cholesterol and particle numbers as a protective measure against reduced lipid transportation to the brain. Lowering particle number may decrease brain health. Maybe it would be better to improve all the other risk factors for heart disease. Jimmy’s lab results might actually be ideal for someone with the APO E4 allele since it reduces heart disease risk but still protects the brain.
Glen-
I think the trade-off is something that is rarely discussed, bwe this the Apoe4/4 story or a host of other topics. High lipoprotein is protective against sepsis and possibly cancer, to say nothing of your point about AZ/Parkinsons. When you talk to lipidologists, they are looking almost exclusively at CVD issues…I think it’s important to keep these other factor in mind. This is a long way of say “I don’t know what the trade-off, real story is here.”
So Robb, tell me again how you can rationalize interviewing a born-again young Earth creationist on a show dedicated to ancestral nutrition…
Evelyn!! It’s been so long, how you doing fatty?
A young Earth creationist on an ancestral health blog? Really, Robb? Perhaps you can explain that one for me.
I think you just laid out the parameters. That sounds remarkably Evlyn-ish BTW.