Download a transcript of this episode here
Topics:
- [3:31] Autoimmune Food Reintroduction For Vitiligo
- [9:36] Glutathione Supplementation
- [14:41] Coconut Oil and Plant Nutrient Absorption
- [17:50] Are All Oils Bad
- [23:44] Tick Causing Meat Allergy
- [26:34] Supplementation For Carb Cravings
- [28:41] A Week In The Life
- [38:42] Exercise Intensity, Aging, and Longevity
- [47:34] mTOR
Questions:
1. Vitiligo question
Heather says:
Hello,
I just finished Robb’s book (which was awesome!) and I have a question about my son. Forgive me if the answer is here, I have scoured this site as well as the forum and couldn’t find what I was looking for. Anyway, my son who is 10 has vitiligo (was diagnosed about a year ago) and we are getting ready to begin the whole 30 program, as well as eliminating some other foods that can be problematic for those with autoimmune (nightshades, etc). My question is, if we want to slowly introduce some foods when the 30 days is complete, how will we know which foods are a problem for him. Someone with rheumetoid arthritis will notice pain fairly quickly and be able to see which foods give them problems and which ones don’t. For someone with vitiligo, the pigment doesn’t disappear or reappear that quickly. I don’t want to eliminate any foods unless they absolutely cause problems for him… just not sure how we can determine which foods those are since the process *I think* would be so much slower for someone with vitiligo. Thank you so much for any help you can provide.
2. acetyl glutathione – rocks or sucks?
Ben says:
Hi Grobb,
Yep I’ve listened to every podcast, you guys are the greatest, etc. etc. etc. etc.
Short and sweet – recently seen acetyl glutathione advertised as actually bioavailable and effective for oral supplementation. Searched pubmed / Dr. Google and ended up more confused rather than less.
Bottom line:
1. Is this an effective way to supplement glutathione?
2. Is it even advisable to supplement glutathione at all, given the poor showing of other antioxidants in non-food form, or at levels beyond what’s found in foods?
Go!
3. Coconut oil not optimal for absorption of plant nutrients?
gwarm says:
And there can be benefits to eating fat with carotenoid rich foods like sweet potato: http://donmatesz.blogspot.com/2011/01/study-people-prefer-carotene-complexion.html?showComment=1316336713879#c7776632542969406789. I believe it takes only 8-12g total fat for the most carotene absorption, and 40g is required for proper lutein absorption. And coconut fat is probably not ideal fat for proper carotenoid absorption because “It was postulated that carotenoids are kept in the enterocyte and not released until long-chain fatty acids (12:0 –18:0) from a subsequent meal enable carotene packaging
into chylo-microns. No secretion of chylomicrons was
observed after consumption of a medium-chain fatty acid–
containing meal (42).” from ‘carotenoid absorption.pdf’
http://donmatesz.blogspot.com/2011/09/iron-oxidation-inflammation-and-aging.html?showComment=1317771021393#c8829668262778452208
4. misconception about all oil?
Matt From Brooklyn says:
Thanks for making my time on the subway so much more pleasant. Its fun to be the only person, or at least I think, not playing fucking video games or listening to music really loudly and actually doing something with my time.
In ‘Super Immunity” by Dr. Joel Furman, he has a section entitled misconception about olive oil. I will keep the quote short, but he essentially says ALL oil fats are bad. Coconut, olive oil, macadamia, etc….
I quote, “When you consume oil (any type of oil), there are no fat binding fibers remaining from the original oil source, That means all the calories are absorbed rapidly and stored away as body fat within minutes.” He also calls all oils processed and says that when you extract the oil, you loose the vast majority of micronutrients and are left with ’empty calories.’
Thoughts?
5. “Tick”-ing Meat Bomb
Mike says:
Hey Robb, Greg & Squatchy, faithful listener to the podcast here since the beginning (I would say religious, but that would imply I only listen once per week ;]). Since you guys did such an awesome job answering my MMA training question back on 123, I figured I would pick your brains on a current news nugget – the recent upsurge in tick-vectored alpha-galactose allergy which causes anaphylaxis ~6 hours after eating non-primate meat (not that I really want to eat primate meat). Given that grass-fed ruminants and pastured pork (bacon makes the world go round) play such a huge role in most successful Paleo templates, how would you adjust recommendations provided most mammals were no longer an option on the table? Up the chicken (what about omega-6s), move to predominately pescetarian fare, start a primate meat importation black market? I’m aware this is a very isolated potential, but from a intellectual perspective I’m intrigued, after a vegetarian fiend, I mean friend, of mine joked of putting an end to factory farming operations by you guessed it, factory farming these ticks and causing a wide-spread release – Damned Vegetarian Inclusion Conspiracy strikes again. Thanks again and hopefully you can give some good insight into the matter. Here’s a link to an article on the matter, in case you guys aren’t familiar with it yet:
http://abcnews.go.com/m/story?id=16610228
6. Supplementing to curb carb cravings per Primal Body Primal Mind
Sage says:
Hey Robb, what is your take on the supplementation discussed in ‘Primal Body Primal Mind’ in reference to reducing carb (sugar) cravings? Supplementing your way through a shitty diet is clearly not the way to go, but perhaps something to facilitate the transition off sugar and getting over the sugar addiction to fully adopt a paleo way of eating. Thanks for your time.
7. A week in the life…
Neil says:
I’ve love to here more about your average days, what you eat and what you do. Mark Sisson did an interesting post on a week in his life http://www.marksdailyapple.com/a-week-in-the-life-of-mark-sisson/ and I found Robb’s comments in sleep deprived podcast #131 where he mentioned that he splits his work day to spend more time outside.
Cheers, Neil. Currently enjoying the amazing Argentinian parrilla’s!
8. Exercise Intensity–Ponce De Leon Gene Shifting Fountain of Youth
Ponce says:
Robb and Greg–You’ve often suggested less is more when it comes to exercise. That is, running marathons, overdone cross-fit may actually reduce longevity and damage health over long term. This NY times article suggest that intense exercise “may activate a muscle stem cell called a satellite cell. With the infusion of these squeaky-clean cells into the system, the mitochondria seem to rejuvenate. (The phenomenon has been called “gene shifting.”” Could long term intensive exercise be the elusive fountain of youth Ponce De Leon sought?
http://www.nytimes.com/2010/11/28/magazine/28athletes-t.html?pagewanted=3
5′ 11″ went from 187 to 165 and 8 percent body fat at 52 thanks to your book/podcast along with cross-fit. Eliminated doctor recommended daily Prilosec and for the first time, learned to enjoy cooking. I feel conflicted with cross-fit where I think the 5-6 day a week beat downs might cause Gene Shifting new cells fending off age or is more likely that intense exercise will increase Cortisol and inflammation accelerating aging?
Thank you—Ponce
9. mTOR
BigPhatEater says:
Simple question with no long involved back story telling you two how awesome you already know you are or in addition how you’ve saved yet another previously miserable human being’s life.
I use USP Modern BCAA’s in conjunction with fasted training and cyclical ketogenic dieting, and USP makes a claim that their BCAA mix targets mTOR. Is upregulation of the mTOR pathway a bad thing from a longevity or cancer viewpoint?
Many thanks and well wishes for your continued successes. As well I can only dream that Greg enjoys my structured concise question and linguistics enough that he waxes ecstatic about them on the podcast. That would be the bees knees. Thanks. BigPhatEater
Hi Robb,
Have you done any write ups on what you are doing in Reno with Specialty Health? I find the fact that you guys invested $60,000 and have seen a $22,000,000 return so far. Do you have anything that gives specific details on how you are calculating the Return on Investment or Savings. My company has been implementing a lot of health initiatives in an attempt to reduce health insurance costs. I feel that they are doing 95% of it right but what your doing in Reno is their missing piece to the puzzle. They have a state of the art gym on site that is free to employees and spouses. They have a central cafeteria that offers grassfed meats and free range chicken (among other things not so great.) They have a clinic and a lab that employees can visit free of cost and are building a fully functioning urgent care center. About the only misstep is that they hired an RD that seem like she gets her information from a crackerjack box. I think that if something like what you are doing in Reno was implemented in a publically traded company it would potentially make headlines. I feel the biggest challenge American companies face these days is the inability to retain talent due to the fact that more and more of the employees compentation increases are going to cover increases in healthcare costs and not actual pay increases as well as the inability to compete globally as healthcare costs are causing the cost of our products to increase. As much info as you can provide would be great. I have to somehow plan a CIA mission to get the info into the hands of our Chief Medical Officer.
Thanks,
D
Thanks for ignoring my comment Robb. The simple use of the search bar at the top of your page and the word “Reno” led me to the information I was looking for. Sorry for being a lazy idiot. My CIA mission is a foot. Someone got wind of my success with paleo and now I have an interview with the RD to be featured in the company health video series. Hopefully as I present your book and the info from your page, more questions will be asked and I can effect some change. FIGHT ON!
D
Hey guys,
Great podcast as usual. Maybe I miss it every time, but I was curious where you record the podcast. Is it an office/gym, or do you do a skype sort of thing?
Ryan
It’s a secret location which changes each time so they can elude the feds
I’m in my office, which is in my gym, and Robb is in his home office. The magic of technology and the bond of our friendship brings us together for this podcast.
Sort of like a Long-Distance’Bromance’…
Rob, in section “A Week In The Life” you say something like: “I usually try to train at noon…”. Ignoring the fact that you usually fail to do so in your current situation, which is understandable (I went throught this not so long ago myself 😉 ), what kind of training would you do if you could? I am particularly interested in the ‘every day’ aspect, I wonder what kind of stuff you think it’s a good idea to do every day.
Really just depends on what spins your propellers! i like lifting, gymnastics and jits. So, tinkering with those daily seems good.
I understand periodization and high reps for hypertrophy, but for a beginner like myself who has not yet achieved your recommendations for getting strong (2x squat 2.5dl 1.5bench etc) would sticking to lower rep range be beneficial? 1 to 3 or 5? I am making monthly progress and am v close to those targets.
I love it, Robb, that you now have a child. I thank the Lord for Zoe and for all the loops, poops, and sleep disturbances she throws into your life. After listening to many, many pre-baby podcasts, I found myself shaking my head often and saying “…well maybe someday when he has a kid he’ll realize solid sleep is a thing of the past.” I don’t care how dark & cold my room is or how consistent is my bedtime, somehow nearly every night one of my children finds his/her way into my bed and disturbs my sleep. I truly feel like you have a much more well-rounded view and are more reasonable in your expectations since Zoe has come into your life. Now just you wait until she goes to school and you have to battle all the crap “food” (class treats, parties, birthdays, food rewards for nothing apparent) they try to give her. Let me tell you that’s when it gets rough! You’ll be the weird parent. It’s okay, though, at least people won’t ask you to help with food committees.
Thanks for all your knowledge and for the entertainment provided by Greg.
From Overland Park, Kansas
Robb, thanks for taking the question about vitiligo and AI. I’ve been on paleo for a couple of years now but some generalized vitiligo has shown up over the past 7 years (I’m 37) and it hasn’t significantly reduced its spread since going full paleo… I have a very high o-3 diet and get lots of southern California sun and the awesome tanning has sort of highlighted the lesions, yet I may also succeeded in some sporadic photo therapy with midday sun – as some spots have regained a little color.
I intend to go full AI protocol on this, but I’m about to get some tests at first thinking this will tell me what sort of inflammation / autoimmune stuff is really going on: ANA, thyroid panel (T3 Free, T4 Free, TAA,TPO,TSH) and HS CRP. Am I missing anything as far as markers for this particular issue, or is vitiligo guaranteed to be AI induced? What about gut bacteria/probiotics? I will shoot a report if I can turn this around.
Ok, so glutathione. I came into neo-paleo this time around courtesy of Bulletproof Exec and Dave Asprey. He’s a great proponent of supplementation (not to mention coffee) and glutathione has been a “thing” for a long time. He feels he has the absorption thing licked by finding liposomal glutathione and studies to back it up. Thoughts?
Here are the details: http://www.ncbi.nlm.nih.gov/pubmed/20535554
I guess for me, one of the great unknowns is what I would even measure as a metric to know whether glutathione use was taking me in the right direction. Can tell you that I don’t look, feel or perform any differently after taking it for a couple months.
My substitute word for “Red” is “Corky”. Feel free to borrow that.
I noticed another poster identified lyposomal glutathione. I have recently been put advise to take both lypospheric (or lyposomal) vit C and glutathione by my MD and Dentist (vit C for mercury amalgam removal). It is interesting and there is a lot of stuff if you look up “lyposomal drug delivery” or similar terms. I have been able to take several grams of vit C with none of the side effects associated with high dosage. Some research (look for Dr. Tom Levy) suggest lyposomal vit c (not sure about glut though) is as effective, if not more, than IV vit C.
I have only been taking vit C for a month and glutathione for past 10 days but I do feel more energetic. My partner noticed I “look better” too. Not exactly scientifically valid…but hey at 35 years old I’ll take what I can get.
However, lyposomal nutrients can be expensive if taking regularly. I am fortunate enough to obtain my supplements for free.
Dear Rob,
Where did you read about the higher protein intake of long living people? I am very interested in this. Could you please send me a link?
love your podcast.
Best,